K-2866 is a selective androgen receptor modulator (SARM) developed by a Memphis pharmaceutical company called GTx INC.
The SARM, which is also known as Enobosarm and GTx-024, is currently being researched for its ability to help prevent muscle loss, muscle wasting, and overall dystrophy.
These conditions are often bought on by cancer and can have debilitating effects on one’s life.
The clinical trials conducted on this SARM show it to be very effective for all the above-mentioned purposes.
The results are so promising that GTx INC is introducing it to the bodybuilding community as an effective measure against muscle loss and wasting. Interest in the drug grew to the point that tons of self-published literature was introduced to show its effects, usage and more.
WHAT MAKES OSTARINE SO SPECIAL?
Anecdotal evidence shows that MK-2866 is one of the safest and most effective anabolic SARMs on the market.
It works similarly to testosterone but without any of the adverse side effects like messing with the natural test production.
Instead, this SARM focuses on increasing natural androgenic activity in bone tissues and muscle.
When taken in conjunction with a strict training regime and a balanced healthy diet, MK-2866 can have similar effects to a cycle of Dianabol or Test-E but without any of the negative side effects.
It doesn’t have any effect on the prostate, the liver or the brain.
That’s what the supplement manufacturers’ claim, but there’s no telling how much of this “evidence” is true. Keep in mind that they’re trying to sell a product so they’re obviously going to market it as an anti-catabolic and anabolic supplement without the adverse side-effects that you’d expect.
The following information is a summary of the available clinical and scientific data on the effectiveness of Ostarine on fighting and/or preventing muscle-wasting.
INCREASES MUSCLE MASS AND BOOSTS STRENGTH
Research is on-going to determine the effects of Ostarine on cancer patients and elderly persons that experience muscle loss and muscular dystrophy.
For instance, a clinical trial with MK-2866 was conducted with a healthy group of 120 elderly individuals who were given 3mg of Ostarine per day for 12 weeks.
At the end of the trial, the individuals experienced improved fitness and more lean muscle mass than before. The group that was given 3mg gained a total of 1.3kg lean body mass (2.8 lbs).
The most notable fact was that they also lost 0.6kg (0,3 lbs) fat mass whilst on Ostarine. So they gained muscle and lost fat.
At the end of the trial, the individuals experienced improved fitness and more lean muscle mass than before. The group that was given 3mg gained a total of 1,3kg lean body mass (2.8 LBS).
It’s important to note here that no steroid-like side-effects or risks were observed, and MK-2866 only works when taken in the mentioned dosage, while lower doses don’t show the same effects.
In another clinical trial, 159 cancer patients were split into two groups, with one given 1mg of MK-2866 and another 3mg of MK-2866 per day for 4 months.
At the end of the trial period, both groups showed increased lean muscle mass without any adverse side effects.
In yet another study, rats that were given MK-2866 orally showed that the body easily assimilates and distributes this SARM. Results also showed that it’s quickly eliminated through detox pathways.
With that said, large-scale studies have yet to be conducted to show the effects on MK-2866 on cancer patients that are experiencing muscle loss.
HELPS WITH BONE HEALTH
It’s common to experience poor bone health as we age due to the deterioration of bone-protective sex hormones in the body.
This often leads to conditions like osteoporosis and other bone diseases. One way to fight such deterioration is to improve bone mineralization and increase muscle mass.
The latter is even more important because muscle mass plays a huge role in strengthening the skeletal system and improving bone strength.
Ostarine has a whole host of benefits to offer including the prevention of bone diseases and promoting speedy recovery from bone fractures.
However, these claims about MK-2866 are supported only by animal studies and there are no human studies to corroborate them.
PROTECTS HEART HEALTH
A clinical study involving 120 healthy subjects of advanced age showed that Ostarine can help lower bad HDL cholesterol levels as well as blood fats like triglycerides. These results were based on a daily dosage of 1 to 3mg per day which helped to maintain healthy lipid levels.
This is crucial for the prevention of heart disease, and these results show us that Ostarine may be a good idea for heart disease sufferers who are dealing with muscle wasting.
INCREASES INSULIN RESISTANCE
Based on the same study mentioned above, Enobosarm can lower blood glucose and increase insulin resistance. These are the same effects that anti-diabetic drugs like metformin show. Additional research is required to prove the benefits of Enobosarm on metabolic syndrome and diabetes but the data is promising.
HOW TO USE MK-2866
There is no one size fits all approach when it comes to the usage of MK-2866. Some bodybuilders prefer to use it on its own for purposes of body re-composition, while others like to stack SARMs.
MK-2668 has been compared to juicing because of its effectiveness at simultaneously increasing lean muscle mass, strength and fat burning. It’s a triple threat whose effects can be observed on daily dosages of 15 mg to 25 mg taken for 12 weeks.
This SARM has a half-life of 24 hours which means you only need to take one dose a day for the best results.
It’s not uncommon to experience 7lbs of muscle gains on Ostarine, but it’s possible to do even better when you pair the SARM with a strict diet.
THE CUTTING PHASE
A lot of bodybuilders prefer to use MK-2866 during the cutting phase because of its superior muscle protective abilities.
To get the most out of it though, you need to use up more calories than you consume.
Make sure to eat a protein-rich diet to help maintain lean muscle mass, prevent calorie deficit and maintain a high metabolism. When you combine this strategy with high-intensity interval training (HIIT) you’ll constantly burn fat and achieve your goals faster
However, it’s important to avoid getting a low metabolism as that will make it doubly hard to burn fat. At the end of the day, you want to protect your metabolism and muscle mass as much as you can during the cutting phase.
A dosage of 12 to 25mg taken for a cycle of 4 to 6 weeks can go a long way in helping you achieve this.
Research shows that taking just 1 to 2 mg of Ostarine for 12 weeks can increase lean muscle mass by 3 lbs. without maintaining a strict exercise or diet regime.
This shows that MK-2866 can increase lean muscle mass on its own without any dietary changes.
For the best results during the bulking phase, it’s recommended to take this SARM in dosages of 15mg to 25 mg per day for 4 to 6 weeks.
PERSONAL EXPERIENCE WITH BULKING ON OSTARINE
When I used MK-2866 for my bulking cycle I gained a significant amount of muscle.
I didn’t use a lot, because I wanted to test out what the effects were of this compound. So I stuck by 10mg a day for 12 weeks total.
The things I noticed instantly was increased endurance and drive in the gym. All my exercises were done very easy and I could do much more sets than normal.
I also noticed an increase in vascularity, even when I was in a bulking stage.
At the end of my cycle, I gained a solid 5-6kg (13 lbs). In my opinion, Ostarine is a good compound for gaining lean muscle and preserving muscle. But, there are better compounds like LGD-4033 or RAD-140 for muscle mass.
USING MK-2866 TO TREAT INJURIES
Injuries are an unavoidable aspect of training and often happen as a result of using the wrong training methods, having an improper recovery routine, and/or overtraining.
That’s why it’s so important to keep the structure of the joints protected, and you can do this by strengthening the tendons and ligaments and maintaining proper form while lifting.
This will help you continue training hard and challenging yourself without running into unnecessary injuries.
Thanks to its bone-strengthening properties, MK-2866 has been used to heal osteoporosis and even prevent injuries.
The most beneficial dosage of Ostarine to take when treating injuries is 12.5 mg per day. Some researchers will also combine it with Ibutamoren.
MK-2866 works great when used in conjunction with a strict dieting regime, as it helps increase muscle mass while promoting proper strength maintenance.
The best way to enhance fat loss and muscle mass is to cycle MK-2866 with another SARM like GW-501516 (Cardarine) during the cutting phase.
This will help increase cardiovascular endurance in order to enhance results. To achieve this, it’s recommended to take daily dosages of 20mg of GW-501516 and 25mg of MK-2866 together during the cutting phase.
MK-2866 SIDE EFFECTS
So far, research shows that MK-2866 doesn’t come with any side-effects.
That’s because it doesn’t have an estrogenic nature. No user or study has reported any health issues either like bloating, water retention, liver toxicity, prostate problems, high blood pressure or cardiovascular issues.
However, anecdotal evidence suggests that taking MK-2866 in high dosages for 8 to 12 weeks can lead to lowered testosterone levels. The good news is that this effect is only temporary and testosterone levels should get back to normal 3 to 4 weeks after stopping the intake of the SARM.
MK-2866 is a powerful and effective SARM which has the ability to improve strength, endurance, and lean muscle mass while healing several health conditions.
It’s versatile enough for use in the cutting and bulking phases and it has no recorded side effects.
To get the most out of MK-2866, it’s recommended to take it in dosages of 20 mg to 25 mg per day. You can also stack it with other SARMs like GW-501516 to achieve better fat loss and improved muscle mass.